Scientific publications
To assess the relevance and prospects of technologies and products

  • Probiotic for livestock
  • Probiotic for poultry
  • Probiotic for pig
  • Astaxanthine for livestock
  • Astaxanthine for human
  • Microbiological protein
Probiotic for cattle.
Mycotoxins and Their Biotransformation in the Rumen: A Review
Backovic A., Roganovic T., Popovic A. 2014. Trial#200: Experimental evaluation of effect of TURVAL 0 (lactic yeast sprayed) on the quality and quantity of produced milk on the territory of Vojvodina (northern Serbia) // Lab. Turval.
Intanoo M., Kongkeitkajorn MB., Suriyasathaporn W., Phasuk Y, Bernard JK., Pattarajinda V. 2020. Effect of supplemental Kluyveromyces marxianus and Pichia kudriavzevii on Aflatoxin M1 excretion in milk of lactating dairy cows // Animals, 10 (4), 709
Kmet V., Jonecova Z., Stachova M. 1992. The effect of pectinolytic yeasts on rumen microflora // J. Anim. Feed Sci., 1 (2), 165 – 170
Lui С., Valles P. 1998. Trial#44: Experimental evaluation of improving effect of TURVAL 4 cattle probiotic on fattening process yield // Lab. Turval.
Lui С., Valles P. 1998. Trial#46: Effects of turval 4 cattle (probiotic) on quality and quantity of milk production // Lab. Turval.
Martínez M.P., Magnoli A.P., González Pereyra M.L., Cavaglieri L. 2019. Probiotic bacteria and yeasts adsorb aflatoxin M1 in milk and degrade 1 it to less toxic AFM1-metabolites // Toxicon, 172: 1-7
Nooraee S.E., Alimon A.R., Ho Y.W., Abdullah N. 2010. Characterization of Kluyveromyces marxianus as a potential feed additive for ruminants // Lett Appl Microbiol, 50(6): 578-584
Probiotic for poultry.
Hao-Yang S., In-Ho K. 2019. Dietary supplementation of mixed yeast culture derived from Saccharomyces cerevisiae and Kluyveromyces maxianus: effects on growth performance, nutrient digestibility, meat quality, blood parameters, and gut health in broilers // J. Poult. Sci., 56: 140-147
Zhong S., Liu HI., Zhang HI., Han TI., Jia HI., Xie YI. 2016. Effects of Kluyveromyces marxianus isolated from Tibetan mushrooms on the plasma lipids, egg cholesterol level, egg quality and intestinal health of laying hens // Brazilian J. of Poult. Sci., 18, N2: 261-268
Wang W., Li Zh., Lv Z., Zhang B., Lv H., Guo Yu. 2017. Effects of Kluyveromyces marxianus supplementation on immune responses, intestinal structure and microbiota in broiler chickens // PLoS ONE 12(7): e0180884
Wang W., Li Zh., Gan L., Fan H., Guo Yu. 2018. Dietary supplemental Kluyveromyces marxianus alters the serum metabolite profile in broiler chickens // Food Funct., 9(7): 3776-3787
Probiotic for pigs.
Different swine trials of probiotic Turval
Yeast extract complex as non-antibiotic functional product in weaning pigs Santi Devi Upadhaya, Yang Jiao, and In Ho Kim
Effect of time and dietary supplementation with processed yeasts (Kluyveromyces fragilis) on immunological parameters in weaned piglets
Healthy rearing with a novel hydrolysed yeast
Astaxanthin as a pigment for livestock.
To give commercial (red) color to aquaculture (red fish, shrimp, crustaceans). At the moment, synthetic astaxanthin is used to give the red color to pet foods, but increasing consumer awareness and concern from regulators is leading to an increase in interest in organic pet foods with natural astaxanthin and the emergence of start-ups developing this direction.
  • aquafeeds
To give color (and useful properties) to the yolk of the egg, up to red.
  • 72507b182ba6c&pid=1-s2.0-S003257911935597X-main.pdf
A number of companies have used these properties to produce eggs enriched with astaxanthin, and having all the useful properties of the latter (for example, Premia, Onzen, Kenkori). In 2020, (Singapore) entered the market. In addition to the beautiful color of the yolk, this product, according to the manufacturer, also has all the positive effects of astaxanthin and is additionally enriched with vitamins, omega 3 and organic selenium.
  • study-to-validate-health-claims-of-astaxanthin-fortification karotinoidov/viewer
Astaxanthin as an antioxidant for livestock.
For aquaculture. Allows you to withstand oxidative stress in conditions of tight fit in RAS. It has a positive effect on survival, growth, reproductive ability, stress resistance, disease resistance and expression of genes associated with immunity.
For a bird. Enhances poultry immunity, improves survival and product quality, as well as the shelf life of eggs
Increased spermatogenesis in animals. Increases spermatogenesis and preservation of frozen sperm. The addition of astaxanthin to the diet of bulls in summer improved sperm quality by improving antioxidant activity and modulating mitochondrial gene expression.
Reduces the effects of heat stress on animal reproduction. Improves embryonic development of cattle disturbed by heat stress.
Astaxanthin for humans
Astaxanthin is the most powerful antioxidant in the world.
Chemical formula: C40H52O4.
Some results of human exposure studies.
Antioxidant and anti-inflammatory activity. Astaxanthin increases the stability of cell membranes by preventing the penetration of substances that promote lipid peroxidation through the lipid layer, and may also provide additional protection against damage caused by free
radicals. When taking astaxanthin, a clinically significant antioxidant effect has been shown, especially in groups susceptible to oxidative stress (smokers, obese and overweight people). Studies have shown that the antioxidant capacity of astaxanthin is 6000 times higher than that of vitamin C, 800 times higher than that of coenzyme Q10, 550 times higher than that of green tea catechins, 75 times higher than that of alpha lipoic acid.
  • about-king-carotenoids/
  • lipophilic_antioxidants_against_singlet_oxygen_using_chemiluminescence_detection_system
Antitumor activity. In a study conducted on human colon cancer cells, the ability to inhibit the growth of cancer cells and promote apoptosis was revealed. Animal experiments have also shown significant antitumor activity of astaxanthin compared to other carotenoids such as canthaxanthin and β-carotene, as well as its ability to suppress the growth of tumor cells and stimulate immunity to fight cancer in rats and mice.
  • %20Antitumor%20activity%20of%20astaxanthin%20and%20its%20mode%20of%20action.pdf
Positive effect on the condition of the skin. In a small group study (30 healthy women for 8 weeks at 6 mg per day in the form of a dietary supplement and 2 ml per day applied to the skin; a second placebo study on 36 men) showed a positive effect on smoothing wrinkles, hydration, skin tone, elasticity, smoothness, puffiness and age spots, moisturizing dry skin, disappearance of acne. There is evidence that astaxanthin may help prevent age spots.
Boosting the immune system Astaxanthin supplementation increased the total number of T- and B-cells relative to placebo, as well as the cytotoxic activity of natural killer cells
Cognitive functions. There is evidence of a positive effect of astaxanthin in terms of such indicators as the suspension of the degradation of cognitive functions caused by age-related changes in people with "forgetfulness", a positive trend was noted during the course of the disease, an improvement in the ability to remember in mice.
Positive effect on vision. A positive effect of astaxanthin on visual acuity was noted even in healthy people, as well as a decrease in eye fatigue, a positive effect in senile farsightedness due to an improvement in the contractility of the papillary muscle. A growing body of evidence suggests that astaxanthin is effective in the prevention and treatment of a number of eye conditions. On the effectiveness of this carotenoid in diseases of the retina, disorders of the surface of the eye, uveitis, cataracts and asthenopia
reported in numerous animal and human studies.
Increases male fertility. It can reduce lipid peroxidation, improve morphology, increase the concentration and motility of human spermatozoa.
Major industrial sources of astaxanthin
Synthetic from petroleum products (used only for animals, as a pigment for aquaculture)
Natural (for animals and humans)
a. microalgae
b. yeast
The problem with the widespread use of microalgal astaxanthin for both humans and animals is its price. The use of yeast as a source of astaxanthin can significantly reduce the cost of this substance. In addition, astaxanthin in yeast biomass has additional qualities: the presence of B vitamins, pre- and probiotic properties. The source of astaxanthin is the Phaffia Rodozyma yeast family. The astaxanthin product in yeast biomass from Protein FeedBioTech differs from the products of global competitors ((Israel) and (China)) in a higher astaxanthin content and lower cost due to a highly productive strain and innovations in the design of the fermenter.

As natural pigments. For creating
functional products with antioxidant and energy properties: drinks, bars, etc.
  • (the result of a study of the coloring of milk with astaxanthin from microalgae)

Creams and serums that prevent UV aging, leveling the negative effects of free radicals.
Yeast protein
Alternative feed ingredients in a world of volatile fishmeal supply
Future Fish Feed: Forecasting Alternative Aqua Feed Ingredients
Made on