Astaxanthin is the most powerful antioxidant in the world.
Chemical formula: C40H52O4.
Some results of human exposure studies.
Antioxidant and anti-inflammatory activity. Astaxanthin increases the stability of cell membranes by preventing the penetration of substances that promote lipid peroxidation through the lipid layer, and may also provide additional protection against damage caused by free
radicals. When taking astaxanthin, a clinically significant antioxidant effect has been shown, especially in groups susceptible to oxidative stress (smokers, obese and overweight people). Studies have shown that the antioxidant capacity of astaxanthin is 6000 times higher than that of vitamin C, 800 times higher than that of coenzyme Q10, 550 times higher than that of green tea catechins, 75 times higher than that of alpha lipoic acid.
- https://wholefoodsmagazine.com/supplements/features-supplements/astaxanthin-what-you-need-know- about-king-carotenoids/
- https://www.sciencedirect.com/science/article/pii/S000527369700182X?via%3Dihub
- https://www.sciencedirect.com/science/article/abs/pii/S000398611000305X?via%3Dihub
- https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201000414
- https://www.sciencedirect.com/science/article/pii/S0955286307001817?via%3Dihub
- https://www.researchgate.net/publication/285255302_Quenching_activities_of_common_hydrophilic_and_ lipophilic_antioxidants_against_singlet_oxygen_using_chemiluminescence_detection_system
Antitumor activity. In a study conducted on human colon cancer cells, the ability to inhibit the growth of cancer cells and promote apoptosis was revealed. Animal experiments have also shown significant antitumor activity of astaxanthin compared to other carotenoids such as canthaxanthin and β-carotene, as well as its ability to suppress the growth of tumor cells and stimulate immunity to fight cancer in rats and mice.
- https://pubmed.ncbi.nlm.nih.gov/19423215/
- https://europepmc.org/article/med/10470126
- https://pubmed.ncbi.nlm.nih.gov/19645817/
- https://tahomaclinic.com/Private/Articles3/Astaxanthin/Jyonouchi%202000%20- %20Antitumor%20activity%20of%20astaxanthin%20and%20its%20mode%20of%20action.pdf
Positive effect on the condition of the skin. In a small group study (30 healthy women for 8 weeks at 6 mg per day in the form of a dietary supplement and 2 ml per day applied to the skin; a second placebo study on 36 men) showed a positive effect on smoothing wrinkles, hydration, skin tone, elasticity, smoothness, puffiness and age spots, moisturizing dry skin, disappearance of acne. There is evidence that astaxanthin may help prevent age spots.
- https://ojs.ptbioch.edu.pl/index.php/abp/article/view/2168
Boosting the immune system Astaxanthin supplementation increased the total number of T- and B-cells relative to placebo, as well as the cytotoxic activity of natural killer cells
- https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-7-18
Cognitive functions. There is evidence of a positive effect of astaxanthin in terms of such indicators as the suspension of the degradation of cognitive functions caused by age-related changes in people with "forgetfulness", a positive trend was noted during the course of the disease, an improvement in the ability to remember in mice.
- https://link.springer.com/article/10.1007/s10653-007-9117
- https://www.jstage.jst.go.jp/article/jcbn/44/3/44_08-238/_article
Positive effect on vision. A positive effect of astaxanthin on visual acuity was noted even in healthy people, as well as a decrease in eye fatigue, a positive effect in senile farsightedness due to an improvement in the contractility of the papillary muscle. A growing body of evidence suggests that astaxanthin is effective in the prevention and treatment of a number of eye conditions. On the effectiveness of this carotenoid in diseases of the retina, disorders of the surface of the eye, uveitis, cataracts and asthenopia
reported in numerous animal and human studies.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281326/
Increases male fertility. It can reduce lipid peroxidation, improve morphology, increase the concentration and motility of human spermatozoa.
- http://www.asiaandro.com/Abstract.asp?doi=10.1111/j.1745-7262.2005.00047.x https://webcache.googleusercontent.com/search?q=cache:eROZDpg0qcAJ:https://zenodo.org/record/3524253/files/33537.pdf+&cd=13&hl=ru&ct=clnk&gl=ru
Major industrial sources of astaxanthin
Synthetic from petroleum products (used only for animals, as a pigment for aquaculture)
Natural (for animals and humans)
a. microalgae
b. yeast
The problem with the widespread use of microalgal astaxanthin for both humans and animals is its price. The use of yeast as a source of astaxanthin can significantly reduce the cost of this substance. In addition, astaxanthin in yeast biomass has additional qualities: the presence of B vitamins, pre- and probiotic properties. The source of astaxanthin is the Phaffia Rodozyma yeast family. The astaxanthin product in yeast biomass from Protein FeedBioTech differs from the products of global competitors ((Israel) and (China)) in a higher astaxanthin content and lower cost due to a highly productive strain and innovations in the design of the fermenter.
As natural pigments. For creating
functional products with antioxidant and energy properties: drinks, bars, etc.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348322/ (the result of a study of the coloring of milk with astaxanthin from microalgae)
- https://www.sciencedirect.com/science/article/abs/pii/S0308814613000320?via%3Dihubhttps://zeleniy.club/magazin/detox-batonchik-so-vkusom-mango-yoo-go/
Creams and serums that prevent UV aging, leveling the negative effects of free radicals.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946307/
